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FAPA - Familial Adenomatous Polyposis Association The Belgian Polyposis Registry

Journal Volume 74 - 2011
Issue Fasc.3 - Symposium
Author(s) A. Kartheuser, S. Laurent, D. Franchimont, E. Van Cutsem
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(1) Belgian Polyposis Project, Familial Adenomatous Polyposis Association (FAPA), Brussels ; (2) General Secretary of the FAPA, Colorectal Surgery Unit, Department of Abdominal Surgery and Transplantation, Cliniques Universitaires St-Luc, Brussels ; (3) Treasurer of the FAPA, Digestive Oncology, Ghent University Hospital, Gent ; (4) Vice-President of the FAPA, Gastroenterology Department, Erasme University Hospital, Brussels ; (5) President of the FAPA, Digestive Oncology Unit, University Hospital Gasthuisberg, Leuven.

Familial adenomatous polyposis (FAP) is an auto- somal dominant disease that affects about 1 in 10 000 to 1 in 8 000 individuals. The underlying genetic defect is a mutation in the APC (Adenomatous Polyposis Coli) gene. If left untreated, this condition inevitably leads to colorectal cancer and a nationwide and systematic screening for asymptomatic gene carriers is therefore of paramount importance.

© Acta Gastro-Enterologica Belgica.
PMID 22103046